This hand colored scanning-electron-micrograph shows Hep-2 (ATCC CCL-23) immortalized carcinoma cells.
Human epithelial type 2 (HEp-2) cells, considered to originate from a human laryngeal carcinoma, allow recognition of over 30 different nuclear and cytoplasmic patterns that are given by upwards of 50 different autoantibodies are associated with various autoimmune conditions.
Hep-2 are adherent epithelial cells growing in aggregates and as single cells. Originally, Hep-2 was derived from a human larynx carcinoma of a 56-year-old black patient. However, a genetic analysis reavealed that Hep-2 is indistinguishable from HeLa (human cervix carcinoma), which means that the cell line must have been contaminated with HeLa. Nevertheless, Hep-2 is commonly used in the field of oncology and e.g. provides a particularly useful system for the study of measles, because of its growth characteristics in media free human serum.
The original work has a size of 180 x 135 cm, limited to 5 pieces.