The malignant social network: Cell-to-cell communication in canc
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Cellular Islands: Cell-to-cell communication (H. sapiens)

Homo sapiens

Magnification: 667:1

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Tumors contain a vastly complicated cellular network that relies on local communication to execute malignant programs. The molecular cues that are involved in cell-cell adhesion orchestrate large-scale tumor behaviors such as proliferation and invasion. We have recently begun to understand that many tumors contain a high degree of cellular heterogeneity and are organized in a cellular hierarchy, with a cancer stem cell (CSC) population identified at the apex in multiple cancer types.

The original work has a size of 180 x 135 cm, limited to 5 pieces.